18 December 2020

The ABCs of CBD

Since its broad interstate legalization in the federal Farm Bill two years ago, nearly 1 in 3 Americans have used CBD at least once. CBD (cannabidiol) is a compound found in marijuana and hemp. Unlike its cousin THC (tetrahydrocannabinol), CBD does not produce a euphoric high and is responsible for many of the medically interesting properties of cannabinols. CBD is popular for relieving pain and sleep problems, among other things. But what does the science say?

A 2017 report from the National Academies of Sciences, Engineering and Medicine found "substantial evidence" supporting the use of CBD for treating chronic pain, nausea and other side effects of chemotherpy, and the muscle spasms that often accompany multiple sclerosis. It also found "some evidence" that it may be effective for sleep problems, especially apnea, and pain from fibromyalgia.

A 2019 Consumer Reports survey of over 1,000 CBD users found that more than 75% reported being "satisfied" or "very satisfied" with it's effectiveness for pain relief.

The best evidence for the medical use of CBD is in the treatment of seizures associated with three relatively rare seizure disorders. Epidiolex, a CBD-based anti-seizure drug, has been approved by the FDA for this use.

The primary mechanism of action of CBD in the body is believed to be a reduction in cellular inflammation.

There are few side effects connected to CBD. While THC in high doses may cause irregular heart rhythm and hallucination, CBD does not seem to have these effects. CBD can interact with certain OTC and prescription drugs though, particularly blood thinners, statins, antihistamines and antidepressants. If you are taking medication be sure to review your status with your doctor before trying CBD.

And remember, this is a new industry. Quality standards vary wildly and labeling in inconsistent. You can also use a number of different formulations from tinctures to creams to chewable gummies and the dose you receive may vary by delivery mechanism.

Many studies and clinical trails are underway and our understanding of CBD for medical purposes is constantly evolving. The regulatory structure overseeing CBD varies State by State and the market still has a bit of a "wild west" feel to it. If you are planning to try CBD, start with a low does and ease into it until you can see how it works for you. And be sure to research the company you purchase from. There are some very good ones out there. But there is no shortage of CBD scammers either.


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