Exercise and Prostate Cancer

 

Exercise oncology is an evolving science that considers the addition of physical activity regimens to the treatment plans of cancer patients and survivors. Studies in this field demonstrate the significance of exercise for cancer patients during and after treatment. A recent study done at Edith Cowan University in Australia and published in Medicine & Science in Sports & Exercise found that prostate cancer patients undergoing standard androgen deprivation therapy (ADT) who participated in a three-month exercise program including resistance training, aerobic exercise, and protein supplementation had increased levels of OSM, a myokine protein. After applying the OSM serum directly to prostate cancer cells, researchers observed significant suppression of tumor growth. 

While this trial only included 10 patients, the results suggest that exercise-driven myokines can suppress tumor growth and, moreover, the same myokines help fight prostate cancer cells.  These findings also indicate that exercise may promote a cancer suppressive environment within the prostate. 

While the researchers believe that additional studies are needed to clarify the impact of specific exercises on myokine expression, high-intensity resistance training should be included in treatment for any type of cancer. Prostate cancer is the most frequently diagnosed cancer in men in the United States and it is estimated that close to 250,000 prostate cancer diagnoses occured in 2021.  Validation of the potential benefits of easy to implement measures like exercise intervention could give many of these patients a boost in fighting the disease.